Merck has provided a comprehensive guide to help you make a cattle vaccine plan! Below you’ll find information and a handy table all the way from pre-breeding to pre-calving.
Pre-Calving:
- Scours vaccine should be given 3 months prior to calving, followed by a booster dose 3-6 weeks later.
 - This is far enough before calving to minimize the stress and possible effects from handling cattle near calving time.
 - For subsequent calving, revaccinate with a single dose 5-7 weeks before calving
 
Calving:
- Healthy calves can be vaccinated as young as 1 week of age with an intranasal respiratory vaccine against the leading causes of early onset BRD.
 
First Working:
- For calves 1 to 3 months of age, this is a crucial time as maternal antibodies decline. It is important to vaccinate calves for optimal production.
 - Respiratory and clostridial vaccines are administered during this time period.
 - Branding/Turnout
 - If giving a tetanus vaccine when castrating or banding bull calves, two doses are required prior to banding or castration procedure.
 - Pre-weaning
 - Vaccinate calves at 14 to 21 days prior to weaning.
 - Avoid the stressful weaning period to ensure stronger immune response to respiratory and clostridial vaccines prior to the high risk period of weaning.
 - Weaning
 - If you must vaccinate during this time, delay working calves until the stress of weaning is over.
 - It is best to wait until the calves are eating, drinking and most (if not all) have stopped walking and bawling.
 - Parasite treatment should also be performed at this time – depending on the product label instructions.
 
Second Working/ Weaning:
- •f you have followed a pre-weaning or first working schedule, then second working will typically occur 2-6 weeks after the first working, or at weaning.
 
Pre-Breeding:
- All pre-breeding MLV vaccines should be done 14–60 days prior to breeding to avoid any possible side effects or complications that could affect fertility.
 - Consult with your veterinarian before using any vaccine on a pregnant or lactating cow.
 
| ACTIVITY | CATTLE TYPE | CATEGORY OF TREATMENT | MERCK ANIMAL HEALTH VACCINE  | 
|---|---|---|---|
| Pre-Calving | Pregnant Cows | Scours | BOVILIS® GUARDIAN® | 
| Calving | Calves | Respiratory | BOVILIS® ONCE® PMH IN OR BOVILIS® NASALGEN® 3-PMH  | 
| First Working • If giving a tetanus vaccine when castrating or banding bull calves, two doses are required prior to banding or castration procedure.  | Calves | Respiratory Clostridial Clostridial + Tetanus Pinkeye - 6 weeks prior to peak fly and pinkeye season. Follow label directions for booster and booster interval  | BOVILIS® VISTA® ONCE SQ* OR BOVILIS® NASALGEN® 3** OR BOVILIS® NASALGEN® 3-PMH** **For use in calves 1 week of age or older Choose one: BOVILIS® VISION® 7/8 OR BOVILIS® VISION® 7/8 SOMNUS Choose one: BOVILIS® CAVALRY® 9 OR BOVILIS® COVEXIN® 8 Choose one: BOVILIS® PILIGUARD® PINKEYE OR BOVILIS® 20/20 VISION® 7 +/- MORAXELLA BOVOCULI  | 
| Second Working | Heifers/Steers | Respiratory Booster Clostridial Booster Clostridial + Tetanus Pinkeye - 6 weeks prior to peak fly and pinkeye season. Follow label directions for booster and booster interval  | Choose one: BOVILIS® VISTA® ONCE SQ* Choose one: BOVILIS® VISION® 7/8 OR BOVILIS® VISION® 7/8 SOMNUS Choose one: BOVILIS® CAVALRY® 9 OR BOVILIS® COVEXIN® 8 Choose one: BOVILIS® PILIGUARD® PINKEYE OR BOVILIS® 20/20 VISION® 7 +/- MORAXELLA BOVOCULI  | 
| Pre-Breeding | Replacement Heifers/Cows  | Respiratory + Lepto + Vibrio  | BOVILIS® VISTA® 5 VL5 SQ CFP* | 
